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NIH Trial Evaluates Long-Acting HIV Medication for People Unable to Adhere to Strict Daily Regimens

Posted on May 09, 2019

Source: NIH

NIH Trial Evaluates Long-Acting HIV Medication for People Unable to Adhere to Strict Daily Regimens

"LATITUDE study compares monthly injectable antiretroviral therapy to daily oral drugs"


"A clinical trial to evaluate long-acting antiretroviral therapy (ART) for maintaining HIV suppression in people for whom adhering to conventional daily oral ART has been a challenge has begun at research sites across the United States. The study, called Long-Acting Therapy to Improve Treatment Success in Daily Life, or LATITUDE, will help determine whether a combination of two experimental injectable formulations of ART are superior to conventional oral ART in managing HIV infection in this population."

"LATITUDE is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and is being conducted by the AIDS Clinical Trials Group (ACTG), with additional support from the National Institute of Mental Health, the National Institute on Drug Abuse, ViiV Healthcare and the Janssen Pharmaceutical Companies of Johnson & Johnson."

“'Antiretroviral therapy has been transformative in the treatment of HIV. Consistently taking these medications as prescribed helps people to live longer, healthier lives and prevents HIV transmission to sexual partners,' said Anthony S. Fauci, M.D., NIAID Director. 'Unfortunately, for many people who must take any medication regularly, adherence can be difficult, Effective alternative formulations of antiretrovirals, including long-acting injectables, may help people better adapt to HIV treatment.'”

 

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