Administrative Supplement

NIH Administrative Supplements

The purpose of this administrative supplement opportunity is to support innovative research projects, inter-CFAR meetings, and shared instrumentation that address key gaps in HIV/AIDS and will advance the field. This opportunity should build research capacity and be consistent with the recent NIH HIV/AIDS research priorities (NOT-OD-15-137).
The NIH is interested in supplement applications in the following areas:

  1. Methodology and Data Science of HIV
  2. Increasing the Integration of Substance Abuse Services and HIV Prevention and Care
  3. Impact of Food Insecurity on HIV Prevention and HIV Care
  4. Human Mobility and HIV 
  5. Overcoming Barriers to HIV Reservoir Clearance
  6. Equipment for CFAR Core(s)
  7. Inter-CFAR Meetings
  • Supplement awards are for one year
  • The funding amount varies per topic listed above, see the supplement announcement for details
  • Project directors are restricted to early career investigators who have never received an R-series, R01-equivalent or U-series research grants.  Established investigators in non-HIV fields who have never received an NIH research award for HIV/AIDS studies are also eligible. Established investigators can be the project leaders for the core equipment and inter-CFAR meeting topics.
  • The CFAR may not fund studies involving new drugs, treatments, or devices, or off-label use of a licensed drug (this includes healthy volunteer studies where drugs are administered).
  • The CFAR may not fund clinical research studies that include randomization to one or more intervention to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes.
  • Studies involving human subjects may be subject to additional NIH review prior to initiating the study, which may cause delays. Similarly, for studies with any foreign component, additional NIH review and approval is required prior to the initiation of any study procedures. More information can be found here

Please see the Supplement Announcement for full details on the areas of interest. 

We are only allowed to submit a limited number of supplement applications, so please submit a one page Letter of Intent (LOI) to no later than April 8th, 2020. The LOI is used to choose the projects that we will be submitting, so please "sell" your study!
The LOI should include:

  • Application title
  • List of investigators
  • Scientific Area of Interest
  • Aim(s)/Objective(s)
  • Summary of rationale and approach


The CFAR Developmental Core and Executive Committee will select projects to be developed into a full proposal for submission to the NIH.

  • Each CFAR may submit more than one application in topics 1-5 BUT no more than four total applications.
  • CFARs can submit one application the equipment topic. 
  • Each inter-CFAR group is permitted to submit one meeting application. A CFAR can submit more than one if they are submitting on behalf of multiple inter-CFAR groups.
  • The deadline for applications to be received at NIAID is May 18, 2020.
  • The earliest anticipated start date is 7/01/19 but may be delayed due to administrative issues.

The CFAR Grant Development and Implementation Toolkit is available online. It is a great resource that is designed to assist in the completion of HIV related grant submissions and to support the implementation of awarded grants. Our Cores and Scientific Working Groups are also available to assist with your proposal.

Any questions about the awards or the application process can be directed to