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Tenofovir, pregnancy and renal function changes in pregnant women living with HIV

Posted on June 28, 2021

Source: AIDS

Tenofovir, pregnancy and renal function changes in pregnant women living with HIV

Summary:"In this retrospective cohort study of pregnant women living with HIV who received prenatal care at the Johns Hopkins Hospital, both TDF and TAF appear to be safe and without renotoxic effects, but larger prospective cohort studies in pregnant women living with HIV are encouraged."

Abstract:

"This retrospective study of 100 pregnant women living with HIV [66 on tenofovir disoproxil fumarate (TDF) compared to 34 women on tenofovir alafenamide (TAF)] found no significant difference in renal function in pregnant women with HIV receiving TDF versus TAF. Our results demonstrate that, in regard to renal toxicity, both TDF and TAF appear to be safe for pregnant women living with HIV, but larger prospective cohort studies in pregnant women living with HIV are encouraged."

 

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