Posted on April 24, 2018
The HIV Prevention Trials Network (HPTN) is engaged in a large number of trials to reduce the
transmission and acquisition of HIV. The trials are broadly divided into those focused on the
development on non-vaccine HIV prevention agents as pre-exposure prophylaxis (PrEP) and integrated
strategies designed to maximize the effectiveness of available HIV prevention tools. The trials cut across
diverse at-risk populations and vary from exploratory vanguard studies to phase 3 randomized
controlled trials. For further information, please visit the HPTN website at www.hptn.org.
We are eager to continue growing our scientific agenda and, thus, are writing to solicit submission of
new concepts. This call for research concepts is broad and welcomed from either HPTN or non-HPTN
affiliated investigators and can focus on any non-vaccine prevention method. The intent is to focus on
identifying either new prevention interventions or combination of interventions that could have a
positive impact on prevention of HIV transmission or acquisition. These could be vanguard studies
(preparatory studies that aim to identify feasibility of recruitment and retention of potential study
population, feasibility and acceptability of intervention or combination of interventions or exploring HIV
incidence rates in specific population) or definitive phase 2 or 3 clinical trials.
Concepts should be limited to five pages and include the following information: brief background and
rationale, target population, study design, key outcomes, study assessments, estimated sample size and
potential impact on the target population. See the attached template.
Concepts should be received by HPTN by mailing to Kathy Hinson (khinson@fhi360.org) by August 15,
2018. These concepts will then be forwarded to the relevant HPTN scientific committee for review and
prioritization (if more than one concept is reviewed). Following the scientific committee review process,
the concepts will undergo the Network review by the HPTN Executive Committee as per HPTN’s
established process. This process is anticipated to take place during the Fall of 2018. The process will
include feedback to the concept authors.
Should you have any questions, please send your queries to Kathy Hinson at khinson@fhi360.org.
