Posted on November 09, 2020
"A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every eight weeks was safe and more effective than a daily oral PrEP regimen at preventing HIV acquisition among a group of cisgender women. The women, from southern and east Africa, are enrolled in a clinical trial sponsored by the National Institutes of Health. This finding, from a planned interim analysis of study data, marks the first time a large-scale clinical trial has shown a long-acting injectable form of HIV prevention to be highly effective for cisgender women."
"Findings reported earlier this year from a companion study established that the long-acting injectable regimen was safe and more effective than a daily oral PrEP regimen at preventing HIV among cisgender men and transgender women who have sex with men. Both studies are sponsored by NIH’s National Institute of Allergy and Infectious Diseases (NIAID) and conducted by the NIH-funded HIV Prevention Trials Network (HPTN). NIAID is co-funding the trial in cisgender women in a unique partnership with ViiV Healthcare and the Bill & Melinda Gates Foundation. ViiV Healthcare and Gilead Sciences, Inc. are providing study medications."