The mission of the NIH CFAR program is to support multidisciplinary research aimed at reducing the burden of HIV both in the United States and around the globe. The continuing spread of HIV in the US and globally underscores the need for ongoing, nationally coordinated collaborative conduct of basic, clinical, epidemiologic, behavioral, and translational research to improve the prevention, detection, treatment and cure/remission of HIV infection and the associated complications / comorbidities.