The Clinical Laboratory Cores (CLC) will coordinate access to world-class laboratory expertise, testing, training, specimen repositories and Good Clinical Laboratory Practices (GCLP) to HIV researchers where specialized laboratory services are essential to measuring study outcomes
*Pharmacology Laboratory Program (CPAL) ( https://www.hopkinsmedicine.org/clinical-pharmacology/clinical-pharmacology-analytical-lab/)
*Repository Laboratory Program
*Immunology Laboratory Program
*Virology Laboratory Program
“Infectious Disease Laboratory”
“Viral Diagnostic Laboratory”
The CFAR Laboratory Core now has in its Virology Lab the availability to HIV researchers the use of Quanterix Simoa Equipment that can detect extremely low-levels of established disease biomarkers, capturing concentrations down to the femtogram/mL level, and as a result monitor small changes in protein concentrations to accurately measure biomarkers associated with disease progression. In addition, small sample volume requirements allow you to conserve valuable samples. Those wishing to use this equipment are asked to provide their own consumables and have a certain understanding using this type of equipment. For more information, please contact Dr. Deborah Persaud at email@example.com. Those wishing to use the equipment are asked to make a formal request through the CFAR web page by clicking the “Request CFAR Services” button.
The Johns Hopkins NIMH Center: comprises an interdisciplinary research team who has pooled their talents to study the nature of HIV-associated neurocognitive disorders (HAND). Their aim is to translate discoveries of the pathophysiological mechanisms into novel therapeutics for HAND.
NIMH Center Biomarker Core: 1) Assist in the development and monitoring of surrogate markers for HIV-associated neurocognitive disorders (HAND) 2) To provide mentorship and consultation for Neuro-AIDS researchers in the development of clinically useful surrogate markers for HAND and to validate these as predictive and associative markers for cognitive impairment and as surrogate markers for therapeutic effectiveness 3) Assist in the development of small molecule therapeutics by providing consultation on pharamcokinetic/pharmacodynamic considerations for drug development, and conducting pharmacokinetic and analysis of potential drugs and drug metabolites.
For a lab service request or consultation:
Click on “Request CFAR Service” button on left
Please help us:
Remember to acknowledge the CFAR in your publications, abstracts, grant proposals, and presentations.
Continued funding from NIH for the JHU CFAR depends on evidence that we are providing added value to HIV research being done at Johns Hopkins.
If you receive any kind of support from the CFAR, please include an acknowledgement in your publications, presentations, etc. by using the citation examples available here.
If any of the support was for Laboratory specific topics and you have published, presented or submitted a proposal, please send a link to Kristin Bigos (firstname.lastname@example.org) so that we can track and publicize HIV research at JHU.
This workshop will provide an overview of the program, describe successful applications and outline currently available CFAR resources to strengthen your application.View Video
Mechanisms of BCG vaccine-induced HIV infectivity of CD4+ T cells
Energy Expenditure and Aging in HIV
High-throughput pharmacogenetic analysis to direct antiretroviral therapies
Exosomes and extracellular RNA of the cervicovaginal compartment in health, HIV infection, and HIV exposure without infection